Urinary Metabolomics from a Dose-Fractionated Polymyxin B Rat Model of Acute Kidney Injury
E. Locci, J. Liu, G. Pais, A. Chighine, D. A. Kahnamoei, T. Xanthos, A. Chalkias, A. Lee, A. Hauser, J. Chang, N. Rhodes, E. d'Aloja, M. H. Scheetz
This study uses urinary metabolomics in a rat model to show that taurine levels increase on day 1 of polymyxin B treatment and correlate with kidney injury markers.
bioRxiv · May 21, 2021Pharmacology & Toxicology