Evaluation of Dose Fractionated Polymyxin B on Acute Kidney Injury: A Translational In Vivo Model
J. Liu, G. M. Pais, S. N. Avedissian, A. Gilchrist, A. Lee, N. J. Rhodes, A. R. Hauser, M. H. Scheetz
This study evaluates the effect of fractionated polymyxin B dosing on acute kidney injury in rats, finding that thrice-daily dosing caused the most kidney damage.
bioRxiv · Nov 18, 2019Pharmacology & Toxicology