Author

J. C. Fitzgerald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

A. Chalkias· 1 shared A. Gilchrist· 1 shared A. Kumar· 1 shared A. Shaw· 1 shared A. Waddell· 1 shared A. Zuppa· 1 shared E. d'Aloja· 1 shared E. Krysztofinska· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Chalkias

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Author profile →

2 papers

Recent·Most cited

Mapping of a N-terminal α-helix domain required for human PINK1 stabilisation, Serine228 autophosphorylation and activation in cells

P. Kakade, H. Ojha, O. Raimi, A. Shaw, A. Waddell, J. Ault, S. Burel, K. Brockmann, A. Kumar, M. Ahanger, E. Krysztofinska, T. Macartney, R. Bayliss, J. C. Fitzgerald, M. Muqit

This study identifies an N-terminal α-helix domain in PINK1 critical for its stabilization, autophosphorylation, and activation, linking mutations in this region to Parkinson's disease.

bioRxiv · Sep 6, 2021Biochemistry

Urinary biomarker and histopathological evaluation of vancomycin and piperacillin-tazobactam nephrotoxicity in comparison with vancomycin in a rat model and a confirmatory cellular model

G. M. Pais, J. Liu, S. N. Avedissian, T. Xanthos, A. Chalkias, E. d'Aloja, E. Locci, A. Gilchrist, W. C. Prozialeck, N. Rhodes, T. P. Lodise, J. C. Fitzgerald, K. Downes, A. Zuppa, M. H. Scheetz

This study evaluates kidney injury from vancomycin and piperacillin-tazobactam in rats and cells, finding no increased toxicity from the combination compared to vancomycin alone.

bioRxiv · Mar 6, 2019Pharmacology & Toxicology