Author

E. D. Layton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. Seshadri· 2 shared M. S. Aguilar· 2 shared A. J. Minnaard· 1 shared C. A. James· 1 shared C. L. Day· 1 shared C. M. Stein· 1 shared D. L. Cross· 1 shared D. M. Koelle· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

C. Seshadri

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2 papers

Recent·Most cited

MR1-restricted T cell clonotypes are associated with 'resistance' to M.tuberculosis infection

D. L. Cross, E. D. Layton, K. K. Yu, M. T. Smith, M. S. Aguilar, S. Li, H. Mayanja-Kizza, C. M. Stein, W. H. Boom, T. R. Hawn, P. Bradley, E. Newell, C. Seshadri

The paper identifies MR1-restricted T cell clonotypes associated with resistance to M. tuberculosis infection in a cohort of Ugandan individuals.

bioRxiv · Oct 12, 2022 · PreprintImmunology

CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells.

C. A. James, Y. Xu, M. S. Aguilar, L. Jing, E. D. Layton, M. Gilleron, A. J. Minnaard, T. Scriba, C. L. Day, E. H. Warren, D. M. Koelle, C. Seshadri

This study investigates how CD4 and CD8 co-receptors affect the functional avidity and activation of CD1b-restricted T cells specific for mycobacterial lipid antigens, revealing distinct functional profiles and proliferation patterns.

bioRxiv · Oct 17, 2020Immunology