Author

D. M. Koelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:flow cytometry· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

E. H. Warren· 2 shared L. Jing· 2 shared A. C. Wilson· 1 shared A. Gomez· 1 shared A. J. Minnaard· 1 shared A. L. Cunningham· 1 shared A. L. Greninger· 1 shared A. M. H. Towlerton· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

E. H. Warren

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Treponema pallidum periplasmic and membrane proteins are recognized by circulating and skin CD4+ T cells

T. B. Reid, C. Godornes, V. L. Campbell, K. J. Laing, L. C. Tantalo, A. Gomez, T. N. Pholsena, N. A. P. Lieberman, T. M. Krause, V. I. Cegielski, L. A. Culver, N. Nguyen, D. Q. Tong, K. L. Hawley, A. L. Greninger, , D. M. Koelle

The paper identifies Tp-specific CD4+ T cell responses in blood and skin of syphilis patients, showing persistence after treatment and highlighting potential vaccine targets.

bioRxiv · Feb 27, 2024Immunology

T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time

S. Ravishankar, A. M. H. Towlerton, I. L. Tiamiyu, P. Mooka, J. Nankoma, J. Kafeero, D. Mubiru, S. Sekitene, L. D. Aicher, C. P. Miller, D. G. Coffey, L. Okoche, P. Atwinirembabazi, J. Okonye, J. White, , E. H. Warren

The paper identifies KSHV- and HIV-specific T-cells in KS tumors and shows they persist over time and coexist with immunosuppressive macrophages.

bioRxiv · Feb 6, 2024 · PreprintImmunology

Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice

W. J. Ouwendijk, P. Roychoudhury, A. L. Cunningham, K. R. Jerome, D. M. Koelle, P. R. Kinchington, I. Mohr, A. C. Wilson, G. M. G. M. Verjans, D. P. Depledge

The paper reanalyzes scRNA-Seq data and finds that HSV-1 latency in non-neuronal ganglionic cells is not supported, attributing the previous findings to technical artifacts.

bioRxiv · Jul 17, 2023Microbiology

CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells.

C. A. James, Y. Xu, M. S. Aguilar, L. Jing, E. D. Layton, M. Gilleron, A. J. Minnaard, T. Scriba, C. L. Day, E. H. Warren, D. M. Koelle, C. Seshadri

This study investigates how CD4 and CD8 co-receptors affect the functional avidity and activation of CD1b-restricted T cells specific for mycobacterial lipid antigens, revealing distinct functional profiles and proliferation patterns.

bioRxiv · Oct 17, 2020Immunology