Author

W. H. Boom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Assay:DNA methylation· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

H. Mayanja-Kizza· 3 shared C. Stein· 2 shared S. Gagneux· 2 shared C. M. Stein· 1 shared C. Seshadri· 1 shared C. V. Harding· 1 shared C. Wejse· 1 shared D. Brites· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersImmunology

H. Mayanja-Kizza

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis

K. A. Dill-McFarland, J. D. Simmons, G. J. Peterson, F. K. Nguyen, M. Campo, P. Benchek, C. Stein, T. Vaisar, H. Mayanja-Kizza, W. H. Boom, T. Hawn

The paper identifies epigenetic methylation differences in lipid and cholesterol pathways associated with resistance to TST/IGRA conversion after Mtb exposure.

bioRxiv · Feb 27, 2024 · PreprintImmunology

HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa

E. M. Windels, E. M. Wampande, M. L. Joloba, W. H. Boom, G. A. Goig, H. Cox, J. Hella, S. Borrell, S. Gagneux, D. Brites, T. Stadler

This study uses genomic data and a Bayesian phylodynamic model to show HIV co-infection reduces Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.

bioRxiv · Sep 12, 2023Microbiology

MR1-restricted T cell clonotypes are associated with 'resistance' to M.tuberculosis infection

D. L. Cross, E. D. Layton, K. K. Yu, M. T. Smith, M. S. Aguilar, S. Li, H. Mayanja-Kizza, C. M. Stein, W. H. Boom, T. R. Hawn, P. Bradley, E. Newell, C. Seshadri

The paper identifies MR1-restricted T cell clonotypes associated with resistance to M. tuberculosis infection in a cohort of Ugandan individuals.

bioRxiv · Oct 12, 2022 · PreprintImmunology

TLR2 on CD4+ and CD8+ T cells promotes late control of Mycobacterium tuberculosis infection

S. Reba, Q. Li, S. Onwuzulike, N. Nagy, K. Parker, K. Umphred-Wilson, S. Shukla, C. V. Harding, W. H. Boom, R. E. Rojas

This study shows that TLR2 on CD4+ and CD8+ T cells is important for late control of Mycobacterium tuberculosis infection, but not early control.

bioRxiv · May 19, 2021Immunology

Interaction between host genes and M. tuberculosis lineage can affect tuberculosis severity: evidence for co-evolution

M. L. McHenry, J. Bartlett, R. P. Igo, E. Wampande, P. Bencheck, H. Mayanja-Kizza, K. Fluegge, N. B. Hall, S. Gagneux, S. Tishkoff, C. Wejse, G. Sirugo, W. H. Boom, M. Joloba, S. M. Williams, C. Stein

The paper investigates the interaction between host genetic variants and Mycobacterium tuberculosis lineage to determine their combined effect on TB severity, finding significant interactions that support host-pathogen co-evolution.

bioRxiv · Sep 14, 2019Evolutionary Biology