Peroxiredoxinylation buffers the redox state of the proteome upon cellular stress
G. Seisenbacher, Z. Raguz Nakic, E. Borras, E. Sabido, U. Sauer, E. de Nadal, F. Posas
This study shows that peroxiredoxin Tsa1 in yeast peroxiredoxinylates hundreds of proteins, affecting metabolism and stress resistance, with thioredoxins removing the resulting disulfide bonds.
bioRxiv · Dec 13, 2023Biochemistry