Trans-epithelial Fluid Pumping Performance of Renal Epithelial Cells and Mechanics of Cystic Expansion
M. I. Choudhury, Y. Li, P. Mistriotis, E. E. Dixon, J. Yang, D. Maity, R. Walker, M. Benson, L. Martin, F. Koroma, F. Qian, K. Konstantopoulos, O. M. Woodward, S. X. Sun
This study uses a microfluidic platform to show renal epithelial cells generate hydraulic pressure gradients, with PKD cells showing reversed fluid flow and higher stall pressure.
bioRxiv · Aug 6, 2019Biophysics