IPF AT2 cells are stuck in transition and biophysically dysfunctional
Andrey Krivoy, Daniel Sevilla-Sánchez, Ian T. Stancil, Evgenia Dobrinskikh, Seyedeh Zahra Fotook Kiaei, Rachel Z. Blumhagen, E. Erin Smith, Ivana V. Yang, Carlyne D. Cool, Lior Atia, David A. Schwartz
The paper identifies migratory non-canonical AT2 cells in IPF lung fibrosis, showing they are trapped in developmental transition states that drive fibrosis progression.
bioRxiv · Feb 17, 2026 · PreprintCell Biology