Rachel Z. Blumhagen

The paper identifies migratory non-canonical AT2 cells in IPF lung fibrosis, showing they are trapped in developmental transition states that drive fibrosis progression.

This study shows that Siglec-F protects against elastase-induced lung inflammation and emphysema by regulating airspace macrophages in mice.

This study shows that Siglec-F deficiency reduces fibrosis in bleomycin-induced lung injury by altering gene expression in airspace macrophages.

This study identifies proteomic changes in non-fibrotic lung tissue associated with the MUC5B promoter variant, linking them to fibrosis progression.

The paper introduces RIFT, a method to identify influential rare variants in aggregate association tests, showing higher sensitivity and lower false positive rates compared to existing methods.