Iohexol-measured glomerular filtration rate and urinary biomarker changes between vancomycin and vancomycin plus piperacillin-tazobactam in a translational rat model
J. Chang, G. Pais, S. Marianski, K. Valdez, E. Lesnicki, E. F. Barreto, N. J. Rhodes, P. R. Yarnold, M. H. Scheetz
This study compares kidney function and injury biomarkers in rats treated with vancomycin, piperacillin-tazobactam, or both, finding no additive nephrotoxicity with the combination.
bioRxiv · Mar 9, 2023Pharmacology & Toxicology