Author

N. J. Rhodes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4

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Research Focus:drug response / drug discovery· 3 Organism:rat· 3 Approach:statistical model· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:clinical cohort / trial· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. H. Scheetz· 4 shared J. Liu· 3 shared G. Pais· 2 shared A. Gilchrist· 1 shared A. Lee· 1 shared A. R. Hauser· 1 shared C. A. Peloquin· 1 shared C. Nys· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersPharmacology & Toxicology

M. H. Scheetz

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4 papers

Recent·Most cited

Iohexol-measured glomerular filtration rate and urinary biomarker changes between vancomycin and vancomycin plus piperacillin-tazobactam in a translational rat model

J. Chang, G. Pais, S. Marianski, K. Valdez, E. Lesnicki, E. F. Barreto, N. J. Rhodes, P. R. Yarnold, M. H. Scheetz

This study compares kidney function and injury biomarkers in rats treated with vancomycin, piperacillin-tazobactam, or both, finding no additive nephrotoxicity with the combination.

bioRxiv · Mar 9, 2023Pharmacology & Toxicology

Of Rats and Men, a Translational Model to Understand Vancomycin Pharmacokinetic/Toxicodynamic relationships

M. H. Scheetz, G. Pais, T. Lodise, S. Tong, J. Davis, J. N. O'Donnell, J. Liu, M. Neely, W. Prozialeck, P. Lamar, N. J. Rhodes, T. Holland

The paper links vancomycin toxicity data from a rat model to two human clinical studies, showing rats are more sensitive to kidney injury at therapeutic concentrations.

bioRxiv · Apr 22, 2021Pharmacology & Toxicology

Use of Therapeutic Drug Monitoring to Characterize Cefepime-Induced Neurotoxicity

V. Venugopalan, C. Nys, N. Hurst, Y. Chen, M. Bruzzone, K. Cherabuddi, N. M. Iovine, J. Liu, M. H. Al-Shaer, M. H. Scheetz, N. J. Rhodes, C. A. Peloquin, K. P. Klinker

This study evaluates cefepime-induced neurotoxicity by analyzing trough concentrations, clinical factors, and EEG findings in hospitalized patients.

bioRxiv · Aug 13, 2020 · PreprintPharmacology & Toxicology

Evaluation of Dose Fractionated Polymyxin B on Acute Kidney Injury: A Translational In Vivo Model

J. Liu, G. M. Pais, S. N. Avedissian, A. Gilchrist, A. Lee, N. J. Rhodes, A. R. Hauser, M. H. Scheetz

This study evaluates the effect of fractionated polymyxin B dosing on acute kidney injury in rats, finding that thrice-daily dosing caused the most kidney damage.

bioRxiv · Nov 18, 2019Pharmacology & Toxicology