Global changes in open reading frame dominance of RNAs during cancer initiation and progression
Y. Suenaga, H. Kogashi, K. Nakatani, J. Lin, Y. Hasegawa, K. Kugou, Y. Kawashima, E. Furukawa, K. Okumura, E. Kita, Y. Wakabayashi, M. Kato, M. Kawazu, Y. Hippo
The paper measures ORF dominance in cancer and finds it increases with carcinogenesis, correlates with translation, and blurs coding/noncoding boundaries before metastasis.
bioRxiv · Jun 2, 2023 · PreprintCancer Biology