Author

E. Gomez-Castaneda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. Castellano· 2 shared A. Eddaoudi· 1 shared A. Giustacchini· 1 shared A. Guvenel· 1 shared B. Bea Mascato· 1 shared C. J. Tape· 1 shared C. Munje· 1 shared D. Valverde· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

S. Castellano

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Author profile →

3 papers

Recent·Most cited

Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes

B. Bea Mascato, E. Gomez-Castaneda, Y. E. Sanchez-Corrales, S. Castellano, D. Valverde

This study shows that ALMS1 depletion disrupts TGF-β pathway cross-signalling and affects extracellular matrix and lipid metabolism in fibroblasts.

bioRxiv · Nov 2, 2022Cell Biology

Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy

E. Gomez-Castaneda, S. Rogers, C. Munje, J. Bittencourt-Silvestre, M. Copland, D. Vetrie, L. Hopcroft, H. Jorgensen, T. Holyoake

The paper identifies TKI-independent genes in CML LSC that could be targeted for new therapies, showing that gemtuzumab-ozogamicin and cyclosporine A have stronger effects on CML cells than healthy cells.

Cancers · Oct 26, 2022Peer-reviewedCancer Biology

Enhanced functionality of low-affinity CD19 CAR T-cells is associated with activation priming and a polyfunctional cytokine phenotype

I. M. Michelozzi, E. Gomez-Castaneda, R. V. C. Pohle, F. Cardoso-Rodriguez, J. Sufi, P. Puigdevall-Costa, M. Subraniyam, E. Kirtsios, A. Eddaoudi, S. W. Wu, A. Guvenel, J. Fisher, S. Ghorashian, M. A. Pule, C. J. Tape, , A. Giustacchini

The paper compares low-affinity and high-affinity CD19 CAR T-cells, finding that low-affinity CARs show enhanced activation and cytokine polyfunctionality due to antigen-dependent priming.

bioRxiv · Sep 22, 2020Cancer Biology