Author

J. Fisher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 3 Cancer Biology· 2 Plant Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 8 Assay:bulk RNA-seq· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:mouse· 3

Frequent Co-Authors

A.-r. Collier· 2 shared B. Korber· 2 shared C. J. Tape· 2 shared C. Mazurek· 2 shared D. H. Barouch· 2 shared D. Zamir· 2 shared J. Miller· 2 shared L. Soong· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A.-r. Collier

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Characterization of tomato canal-1 mutant using a multi-omics approach

M. W. Ahchige, J. Fisher, E. Sokolowska, R. Lyall, N. Illing, A. Skirycz, D. Zamir, S. Alseekh, A. R. Fernie

The paper characterizes the tomato canal-1 mutant using multi-omics data, showing that green leaves compensate for impaired SCO2 function through transcriptional upregulation, while white leaves fail to compensate and exhibit stress responses.

bioRxiv · Nov 26, 2023Plant Biology

Neutralization Escape by SARS-CoV-2 Omicron Subvariant BA.2.86

N. Lasrado, A.-r. Collier, N. Hachmann, J. Miller, M. Rowe, E. Schonberg, S. Rodrigues, A. LaPiana, R. Patio, T. Anand, J. Fisher, C. Mazurek, R. Guan, K. Wagh, J. Theiler, , D. H. Barouch

This study evaluates the neutralization escape of the SARS-CoV-2 Omicron subvariant BA.2.86 compared to other variants, finding lower neutralization by antibodies than BA.2 but comparable to circulating variants.

bioRxiv · Sep 4, 2023Microbiology

Waning Immunity Against XBB.1.5 Following Bivalent mRNA Boosters

N. Lasrado, A.-r. Collier, J. Miller, N. Hachmann, J. Liu, M. Sciacca, C. Wu, T. Anand, E. Bondzie, J. Fisher, C. Mazurek, R. Patio, O. Powers, S. Rodrigues, M. Rowe, , D. H. Barouch

This study evaluates the durability of humoral and cellular immune responses to XBB.1.5 after bivalent mRNA boosters, finding waning neutralizing antibody titers but preserved T cell responses.

bioRxiv · Jan 22, 2023 · PreprintImmunology

Alterations in Germinal Center Formation and B Cell Activation during Severe Orientia tsutsugamushi Infection in Mice

C. Gonzales, Y. Liang, J. Fisher, G. Card, J. Sun, L. Soong

This study investigates B cell and germinal center (GC) responses in mice infected with Orientia tsutsugamushi, finding disrupted GC formation and reduced B cell activation at later stages of infection.

bioRxiv · Jan 12, 2023 · PreprintImmunology

OPS-γδ: allogeneic opsonin-secreting γδT cell immunotherapy for solid tumours mediates direct and bystander immunity

D. Fowler, M. Barisa, A. Southern Navarrete, C. Nattress, E. Hawkins, E. Vassalou, A. Kanouta, J. Counsell, E. M. Rota, P. Vlckova, B. Draper, C. J. Tape, K. Chester, J. Anderson, J. Fisher

OPS-γδ cells, engineered to secrete opsonins and stabilized IL15, show enhanced cytotoxicity and bystander activation for solid tumor control.

bioRxiv · Oct 23, 2022 · PreprintImmunology

Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi

J. Thiriot, Y. Liang, J. Fisher, D. H. Walker, L. Soong

This study uses CD-1 mice to model severe scrub typhus caused by Orientia tsutsugamushi, finding they exhibit high susceptibility and a Th1/CD8-skewed immune profile associated with disease severity.

bioRxiv · May 5, 2022Microbiology

European Vintage tomatoes galore: a result of farmers combinatorial assorting/swapping of a few diversity rich loci

J. Blanca, C. Pons, J. Montero-Pau, D. Sanchez-Matarredona, P. Ziarsolo, L. Fontanet, J. Fisher, M. Plazas, J. Casals, J. L. Rambla, A. Riccini, S. Pombarelli, A. Ruggiero, M. Sulli, S. Grillo, , A. Granell

The paper analyzes genetic diversity in European vintage tomatoes, finding low overall diversity but high selective pressure on few loci shaping morphological traits.

bioRxiv · Oct 26, 2021 · PreprintPlant Biology

HOXA9 acts as a regulatory switch in acute myeloid leukaemia and myeloproliferative neoplasms

L. Talarmain, M. A. Clarke, D. Shorthouse, J. Fisher, B. A. Hall

The paper investigates HOXA9's role in AML and MPN, showing it acts as a regulatory switch affecting prognosis and clinical outcomes through interactions with JAK2, TET2, RUNX1, and NOTCH.

bioRxiv · Mar 5, 2021Cancer Biology

Enhanced functionality of low-affinity CD19 CAR T-cells is associated with activation priming and a polyfunctional cytokine phenotype

I. M. Michelozzi, E. Gomez-Castaneda, R. V. C. Pohle, F. Cardoso-Rodriguez, J. Sufi, P. Puigdevall-Costa, M. Subraniyam, E. Kirtsios, A. Eddaoudi, S. W. Wu, A. Guvenel, J. Fisher, S. Ghorashian, M. A. Pule, C. J. Tape, , A. Giustacchini

The paper compares low-affinity and high-affinity CD19 CAR T-cells, finding that low-affinity CARs show enhanced activation and cytokine polyfunctionality due to antigen-dependent priming.

bioRxiv · Sep 22, 2020Cancer Biology

Rora regulates activated T helper cells during inflammation

V. Liora, J. A. Walker, J. Henriksson, Z. Miao, E. Natan, G. Kar, S. Clare, J. L. Barlow, E. Charidemou, L. Mamanova, X. Chen, V. Proserpio, J. Pramanik, S. Woodhouse, A. V. Protasio, , S. A. Teichmann

This study investigates Rora's role in CD4+ T cells during inflammation, finding it regulates lung inflammation and is controlled by IL-33 and CCL7.

bioRxiv · Jul 15, 2020 · PreprintImmunology

The flagellar substrate specificity switch protein FlhB assembles onto the extra-membrane export gate to regulate type three secretion

L. Kuhlen, S. Johnson, A. Zeitler, S. Baurle, J. Deme, R. Debo, J. Fisher, S. Wagner, S. Lea

The paper determines the structure of the FlhB/SctU switch protein in the type three secretion system export gate and shows its role in regulating secretion specificity.

bioRxiv · Jul 4, 2019 · PreprintMicrobiology