Author

E. J. D'Lauro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

J. Beld· 2 shared P. J. Loll· 2 shared C. Guzik· 1 shared K. C. Grasty· 1 shared L. J. Maciunas· 1 shared P. Rotsides· 1 shared S. B. Padrick· 1 shared S. Brady· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

J. Beld

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 9, 2023

The VanS sensor histidine kinase from type-B VRE recognizes vancomycin directly

L. J. Maciunas, P. Rotsides, E. J. D'Lauro…·P. J. Loll

This study shows that type-B VanS from VRE directly interacts with vancomycin, activating its autokinase activity and confirming a direct sensing mechanism for VanS.

DOI 10.1101/2023.07.09.548278

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

BiochemistrybioRxivDec 12, 2022

Structure of VanS from Vancomycin-Resistant Enterococci: A Sensor Kinase with Weak ATP Binding

K. C. Grasty, C. Guzik, E. J. D'Lauro…·P. J. Loll

The paper presents X-ray structures of VanS CA domains from VRE types A and C, revealing weak ATP binding with low millimolar KD values, suggesting a regulatory mechanism for resistance gene expression.

DOI 10.1016/j.jbc.2023.103001

bacteria (other)structural biology

𝕏 PostBluesky