Author

S. B. Padrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

E. T. Spiliotis· 2 shared M. R. Tomasso· 2 shared A. Cavalli· 1 shared A. J. Arribas· 1 shared A. Lupia· 1 shared A. M. Carrasco del Amor· 1 shared A. Stathis· 1 shared B. Bornhauser· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

E. T. Spiliotis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure of VanS from Vancomycin-Resistant Enterococci: A Sensor Kinase with Weak ATP Binding

K. C. Grasty, C. Guzik, E. J. D'Lauro, S. B. Padrick, J. Beld, P. J. Loll

The paper presents X-ray structures of VanS CA domains from VRE types A and C, revealing weak ATP binding with low millimolar KD values, suggesting a regulatory mechanism for resistance gene expression.

bioRxiv · Dec 12, 2022Biochemistry

A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers

F. Spriano, G. Sartori, L. Barnabei, A. J. Arribas, M. Guala, A. M. Carrasco del Amor, M. R. Tomasso, C. Tarantelli, L. Cascione, G. Golino, M. E. Riveiro, R. Bortolozzi, A. Lupia, F. Paduano, S. Huguet, , E. Gaudio

This paper develops EG-011, a first-in-class WASp activator with anti-tumor activity in hematological cancers, including resistant models.

bioRxiv · Nov 25, 2022 · PreprintCancer Biology

Septins mediate a microtubule-actin crosstalk that enables actin growth on microtubules

K. Nakos, M. R. Radler, I. A. Kesisova, M. R. Tomasso, S. B. Padrick, E. T. Spiliotis

This paper identifies septins as mediators of microtubule-actin crosstalk, showing they enable actin growth on microtubules through direct crosslinking and polymerization coupling.

bioRxiv · Feb 15, 2022 · PreprintCell Biology

Production and analysis of a mammalian septin hetero-octamer complex

B. T. DeRose, R. S. Kelley, R. Ravi, B. Kokona, E. T. Spiliotis, S. B. Padrick

This paper produces and characterizes a recombinant mammalian septin hetero-octamer complex, revealing its structure and polymerization behavior.

bioRxiv · Jun 15, 2020Biochemistry