The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase
Y. Zhou, G. A. Phelps, M. M. Mangrum, J. McLeish, E. K. Phillips, J. Lou, C. F. Ancajas, J. M. Rybak, P. M. Oelkers, M. D. Best, R. Lee, T. B. B. Reynolds
The paper identifies CBR-5884 as a potent inhibitor of Candida albicans Cho1, showing fungistatic effects and disrupting in vivo Cho1 function.
bioRxiv · Nov 1, 2023 · PreprintMicrobiology