Genome-wide analysis in Escherichia coli unravels an unprecedented level of genetic homoplasy associated with cefotaxime resistance.
J. P. M. Coolen, E. den Drijver, J. J. Verweij, J. Schildkraut, K. Neveling, W. J. G. Melchers, E. Kolwijck, H. F. L. Wertheim, J. Kluytmans, M. A. Huynen
The paper identifies a −42 C>T mutation in the ampC promoter as significantly associated with cefotaxime resistance in E. coli through genome-wide homoplasy analysis.
bioRxiv · Jun 1, 2020Microbiology