Author

J. Rossen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Tsherniak· 2 shared A. A. Tang· 1 shared A. J. H. Cremers· 1 shared A. Subramanian· 1 shared A. van Heijst· 1 shared B. T. Wong· 1 shared C. Bleeker-Rovers· 1 shared C. C. Mader· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Tsherniak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Non-oncology drugs are a source of previously unappreciated anti-cancer activity

S. M. Corsello, R. T. Nagari, R. D. Spangler, J. Rossen, M. Kocak, J. G. Bryan, R. Humeidi, D. Peck, X. Wu, A. A. Tang, V. M. Wang, S. A. Bender, E. Lemire, R. Narayan, P. Montgomery, , T. R. Golub

The paper identifies non-oncology drugs with anti-cancer activity across 578 cancer cell lines using PRISM, finding that many drugs selectively inhibit cancer cells based on molecular features.

bioRxiv · Aug 9, 2019Cancer Biology

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

J. M. Dempster, J. Rossen, M. Kazachkova, J. Pan, G. Kugener, D. E. Root, A. Tsherniak

The paper describes updates to the Project Achilles processing pipeline for CRISPR screens in cancer cell lines, including quality control improvements and dependency score calculations.

bioRxiv · Jul 31, 2019 · PreprintCancer Biology

Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit

A. J. H. Cremers, J. Coolen, C. Bleeker-Rovers, N. van der Geest-Blankert, D. Haverkate, H. Hendriks, S. Henriet, M. Huynen, E. Kolwijck, D. Liem, W. Melchers, J. Rossen, J. Zoll, A. van Heijst, J. Hopman, H. Wertheim

The paper uses whole-genome sequencing to resolve MSSA outbreaks in a NICU, revealing more accurate transmission chains than traditional methods.

bioRxiv · Apr 13, 2019Microbiology