ATP13A3 Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport
B. Liu, M. Azfar, E. Legchenko, J. A. West, S. Martin, C. Van den Haute, V. Baekelandt, J. Wharton, L. Howard, M. Wilkins, P. Vangheluwe, N. W. Morrell, P. D. Upton
This study identifies ATP13A3 as a polyamine transporter whose deficiency leads to endothelial dysfunction and pulmonary arterial hypertension.
bioRxiv · Aug 29, 2023 · PreprintCell Biology