Author

P. D. Upton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

N. W. Morrell· 2 shared A. Condliffe· 1 shared A. Higuera· 1 shared B. Liu· 1 shared C. Summers· 1 shared C. Van den Haute· 1 shared E. Legchenko· 1 shared E. R. Chilvers· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

N. W. Morrell

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Author profile →

2 papers

Recent·Most cited

ATP13A3 Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport

B. Liu, M. Azfar, E. Legchenko, J. A. West, S. Martin, C. Van den Haute, V. Baekelandt, J. Wharton, L. Howard, M. Wilkins, P. Vangheluwe, N. W. Morrell, P. D. Upton

This study identifies ATP13A3 as a polyamine transporter whose deficiency leads to endothelial dysfunction and pulmonary arterial hypertension.

bioRxiv · Aug 29, 2023 · PreprintCell Biology

Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice

W. Li, L. Long, X. Yang, Z. Tong, M. Southwood, P. Caruso, P. D. Upton, P. Yang, G. Bocobo, I. Nikolic, A. Higuera, R. Salmon, H. Jiang, K. Lodge, K. Hoenderdos, , N. W. Morrell

This study shows that BMP9 protects pulmonary endothelium during inflammation-induced lung injury and that exogenous BMP9 can prevent lung injury in mice.

bioRxiv · May 12, 2020Physiology