Author

E. Lemarchand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Hoyle· 1 shared D. Brough· 1 shared J. P. Green· 1 shared S. M. Allan· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

C. Hoyle

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1 paper

Recent·Most cited

Itaconate and fumarate derivatives exert a dual inhibitory effect on canonical NLRP3 activation in macrophages and microglia

C. Hoyle, J. P. Green, S. M. Allan, D. Brough, E. Lemarchand

This study shows itaconate and fumarate derivatives inhibit both priming and activation of NLRP3 inflammasome in macrophages and microglia, suggesting their therapeutic potential for NLRP3-driven diseases.

bioRxiv · Feb 1, 2021Immunology