Author

E. Lieberman Aiden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:Hi-C· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Maiser· 1 shared A. Presser Aiden· 1 shared A. Vannini· 1 shared D. M. Gilbert· 1 shared D. Weisz· 1 shared E. Cutts· 1 shared H. Harz· 1 shared H. Leonhardt· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Maiser

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Author profile →

3 papers

Recent·Most cited

MCPH1 inhibits condensin II during interphase by regulating its SMC2-kleisin interface.

M. Houlard, E. Cutts, M. S. Shamim, J. Godwin, D. Weisz, A. Presser Aiden, E. Lieberman Aiden, L. Schermelleh, A. Vannini, K. Nasmyth

This paper shows MCPH1 inhibits condensin II during interphase by binding to NCAPG2, preventing chromosome condensation, and demonstrates that this regulation is essential for maintaining chromatin structure.

bioRxiv · Jul 20, 2021Cell Biology

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis

M. Cremer, K. Brandstetter, A. Maiser, S. S. Rao, V. Schmid, M. Guirao-Ortiz, N. Mitra, S. Mamberti, K. N. Klein, D. M. Gilbert, H. Leonhardt, M. C. Cardoso, E. Lieberman Aiden, H. Harz, T. Cremer

The paper shows cohesin-depleted cells undergo endomitosis and rebuild a multilobulated nucleus with functional compartments despite lacking cohesin.

bioRxiv · Sep 14, 2020Cell Biology

De Novo Prediction of Human Chromosome Structures: Epigenetic Marking Patterns Encode Genome Architecture

M. Di Pierro, R. R. Cheng, E. Lieberman Aiden, P. G. Wolynes, J. N. Onuchic

The paper predicts human chromosome structures from epigenetic data, showing that chromatin architecture can be inferred through phase separation-like processes using ChIP-Seq and Hi-C data.

bioRxiv · Aug 7, 2017Biophysics