Author

K. Nasmyth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

J. Godwin· 2 shared J. Rhodes· 2 shared L. Schermelleh· 2 shared A. Presser Aiden· 1 shared A. Rattani· 1 shared A. Vannini· 1 shared B. Rowland· 1 shared D. Mazza· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

J. Godwin

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4 papers

Recent·Most cited

MCPH1 inhibits condensin II during interphase by regulating its SMC2-kleisin interface.

M. Houlard, E. Cutts, M. S. Shamim, J. Godwin, D. Weisz, A. Presser Aiden, E. Lieberman Aiden, L. Schermelleh, A. Vannini, K. Nasmyth

This paper shows MCPH1 inhibits condensin II during interphase by binding to NCAPG2, preventing chromosome condensation, and demonstrates that this regulation is essential for maintaining chromatin structure.

bioRxiv · Jul 20, 2021Cell Biology

Loss of Sister Kinetochore Co-orientation and Peri-centromeric Cohesin Protection after Meiosis I Depends on Cleavage of Centromeric REC8

S. Ogushi, A. Rattani, J. Godwin, J. Metson, L. Schermelleh, K. Nasmyth

The paper shows that cleavage of REC8 in meiosis I is essential for sister kinetochore co-orientation loss and peri-centromeric cohesin deprotection, which are necessary for sister chromatid disjunction.

bioRxiv · Feb 6, 2020Cell Biology

Scc2/Nipbl Hops Between Chromosomal Cohesin Rings After Loading

J. Rhodes, D. Mazza, K. Nasmyth, S. Uphoff

This study shows Scc2/Nipbl dynamically hops between chromosomal cohesin rings after loading, suggesting a post-loading function in DNA loop extrusion.

bioRxiv · May 11, 2017Cell Biology

Cohesin Can Remain Associated With Chromosomes During DNA Replication

J. Rhodes, J. Haarhuis, J. Grimm, B. Rowland, L. Lavis, K. Nasmyth

The paper investigates whether cohesin complexes from G1 phase remain associated with chromatin during DNA replication, finding that they persist in S phase when cohesin turnover is inhibited.

bioRxiv · Apr 4, 2017Cell Biology