Author

E. M. Bouma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. P. I. van de Pol· 4 shared I. A. Rodenhuis-Zybert· 4 shared J. M. Smit· 3 shared B. M. ter Ellen· 2 shared B. Troost· 2 shared D. van Gosliga· 2 shared H. H. van der Ende-Metselaar· 2 shared J. Smit· 2 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersMicrobiology

D. P. I. van de Pol

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5 papers

Recent·Most cited

Moxidectin and ivermectin inhibit SARS-CoV-2 replication in Vero E6 cells but not in human primary airway epithelium cells

N. Dinesh Kumar, B. M. ter Ellen, E. M. Bouma, B. Troost, D. P. I. van de Pol, H. H. van der Ende-Metselaar, D. van Gosliga, L. Apperloo, O. A. Carpaij, M. van den Berge, M. C. Nawijn, Y. Stienstra, I. A. Rodenhuis-Zybert, J. Smit

This study compares the antiviral activity of moxidectin and ivermectin against SARS-CoV-2 in Vero E6 cells and human airway epithelial cells, finding inhibition in Vero cells but not in human cells.

bioRxiv · May 17, 2021Microbiology

Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Replication In Vitro

B. M. ter Ellen, N. Dinesh Kumar, E. M. Bouma, B. Troost, D. P. I. van de Pol, H. H. van der Ende-Metselaar, L. Apperloo, D. van Gosliga, M. van den Berge, M. C. Nawijn, P. H. J. van der Voort, J. Moser, I. A. Rodenhuis-Zybert, J. M. Smit

This study shows resveratrol and pterostilbene inhibit SARS-CoV-2 replication in vitro in multiple cell types, with long-lasting antiviral effects.

bioRxiv · Sep 24, 2020 · PreprintMicrobiology

Chikungunya virus requires an intact microtubule network for efficient viral genome delivery

T. E. Hoornweg, E. M. Bouma, D. P. I. van de Pol, I. A. Rodenhuis-Zybert, J. M. Smit

This study shows that Chikungunya virus requires an intact microtubule network for efficient viral genome delivery during cell entry, enhancing infection.

PLOS Neglected Tropical Diseases · Aug 7, 2020Peer-reviewedMicrobiology

Serotonergic drugs inhibit CHIKV infection at different stages of the cell entry pathway

E. M. Bouma, D. P. I. van de Pol, I. D. Sanders, I. A. Rodenhuis-Zybert, J. M. Smit

This study identifies serotonergic drugs that inhibit CHIKV infection by targeting early stages of the replication cycle, specifically before RNA translation and genome replication.

bioRxiv · Mar 24, 2020Microbiology

Cooperative Chikungunya virus membrane fusion and its sub-stoichiometric inhibition by CHK-152 antibody

J. S. Blijleven, E. M. Bouma, J. Smit, A. M. van Oijen

This study investigates how the CHK-152 antibody inhibits Chikungunya virus fusion by shielding virions and altering kinetic competition at lower pH.

bioRxiv · Mar 18, 2020 · PreprintMicrobiology