Evolutionary BiologybioRxivPreprint
Evolutionary causes of lifespan extension by dietary restriction: linking theory and mechanisms
L. M. Travers, H. Carlsson, E. M. L. Duxbury, A. A. Maklakov
This study tests two hypotheses about how dietary restriction extends lifespan by manipulating autophagy in C. elegans and shows that autophagy is crucial for survival during famine but reduces reproduction.
DOI 10.1101/2020.01.14.904599