H. Carlsson

Sex-specific growth and lifespan effects of germline removal in the dioecious nematode Caenorhabditis remanei

This study shows germline removal increases male lifespan and heat-shock resistance in C. remanei but reduces female growth and does not extend their lifespan.

Beneficial cumulative effects of old parental age on offspring fitness

This study shows that old parental age in C. elegans leads to fitter offspring with faster life-histories, and these effects accumulate over generations but reverse with a single generation of young parent breeding.

Multigenerational downregulation of insulin/IGF-1 signalling in adulthood improves lineage survival, reproduction, and fitness in C. elegans supporting the developmental theory of ageing

Transgenerational fitness effects of lifespan extension by dietary restriction in Caenorhabditis elegans

This study examines the transgenerational effects of dietary restriction on lifespan and fitness in C. elegans, finding both benefits and detriments across generations.

Environmental variation mediates the evolution of anticipatory parental effects

This study shows that anticipatory maternal effects evolve in predictable environments but are lost in unpredictable ones, enhancing offspring fitness in stable conditions.

Rapid environmental change favours the evolution of shorter lifespan

This study shows that rapid environmental temperature fluctuations select for shorter lifespan in nematodes, contradicting classical theory that predicts longer lifespan under variable environments.

Evolutionary causes of lifespan extension by dietary restriction: linking theory and mechanisms

This study tests two hypotheses about how dietary restriction extends lifespan by manipulating autophagy in C. elegans and shows that autophagy is crucial for survival during famine but reduces reproduction.

Cost-free lifespan extension via optimisation of gene expression in adulthood supports the developmental theory of ageing

The paper shows that optimising gene expression in adulthood extends lifespan in C. elegans without fitness costs, supporting the developmental theory of ageing.