Author

E. M. Merten

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Biochemistry· 1

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Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Ghoshal· 1 shared A. L. Mordant· 1 shared C. A. Mills· 1 shared C. Arrowsmith· 1 shared C. E. Cameron· 1 shared D. N. Streblow· 1 shared J. D. Sears· 1 shared J. J. Arnold· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Ghoshal

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1 paper

Recent·Most cited

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

E. M. Merten, J. D. Sears, T. M. Leisner, P. B. Hardy, A. Ghoshal, M. A. Hossain, K. H. Asressu, P. J. Brown, M. A. Stashko, L. E. Herring, A. L. Mordant, T. S. Webb, C. A. Mills, N. K. Barker, J. J. Arnold, , K. H. Pearce

This paper identifies and characterizes RA-0002034, a covalent inhibitor of CHIKV nsP2 protease, showing potent inhibition and selectivity against alphaviruses.

bioRxiv · Mar 22, 2024 · PreprintBiochemistry