Author

E. M. Sontag

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Frydman· 2 shared A. K. Lytton-Jean· 1 shared C. Larabell· 1 shared C. W. Hecksel· 1 shared D. Mankus· 1 shared D. R. Gestaut· 1 shared F. Morales-Polanco· 1 shared G. McDermott· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J. Frydman

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Author profile →

2 papers

Recent·Most cited

An ESCRT-dependent pathway of Nuclear and Cytoplasmic Spatial PQC is coordinated at Nuclear Vacuolar Junctions

E. M. Sontag, F. Morales-Polanco, J.-H. Chen, G. McDermott, P. T. Dolan, D. R. Gestaut, M. A. LeGros, C. Larabell, J. Frydman

The paper identifies an ESCRT-dependent pathway that coordinates nuclear and cytoplasmic protein quality control (PQC) at nuclear-vacuolar junctions, enabling vacuolar clearance of misfolded proteins.

bioRxiv · Dec 1, 2022 · PreprintBiochemistry

Multi-Scale 3D Cryo-Correlative Microscopy for Vitrified Cells

G.-H. Wu, P. G. Mitchell, J. G. Galaz-Montoya, C. W. Hecksel, E. M. Sontag, V. Gangadharan, J. Marshman, D. Mankus, M. E. Bisher, A. K. Lytton-Jean, J. Frydman, K. Czymmek, W. Chiu

This paper introduces a multi-scale 3D cryo-correlative microscopy pipeline for visualizing vitrified cells, demonstrating its application to heat-shocked yeast cells.

bioRxiv · May 21, 2020Cell Biology