Author

M. A. LeGros

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

J.-H. Chen· 2 shared A. R. Dunn· 1 shared C. A. Larabell· 1 shared C. L. Hueschen· 1 shared C. Larabell· 1 shared D. R. Gestaut· 1 shared E. M. Sontag· 1 shared F. Morales-Polanco· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J.-H. Chen

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2 papers

Recent·Most cited

An ESCRT-dependent pathway of Nuclear and Cytoplasmic Spatial PQC is coordinated at Nuclear Vacuolar Junctions

E. M. Sontag, F. Morales-Polanco, J.-H. Chen, G. McDermott, P. T. Dolan, D. R. Gestaut, M. A. LeGros, C. Larabell, J. Frydman

The paper identifies an ESCRT-dependent pathway that coordinates nuclear and cytoplasmic protein quality control (PQC) at nuclear-vacuolar junctions, enabling vacuolar clearance of misfolded proteins.

bioRxiv · Dec 1, 2022 · PreprintBiochemistry

Emergent Actin Flows Explain Diverse Parasite Gliding Modes

C. L. Hueschen, L.-a. Segev Zarko, J.-H. Chen, M. A. LeGros, C. A. Larabell, J. C. Boothroyd, R. Phillips, A. R. Dunn

This study uses single-molecule imaging and modeling to show that F-actin flows in parasites self-organize to produce diverse gliding motility modes.

bioRxiv · Jun 8, 2022Biophysics