Author

E. M. Upton

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. M. Ripley· 1 shared D. K. Meyerholz· 1 shared E. K. Luhmann· 1 shared L. Radoshevich· 1 shared Y. Zhang· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

B. M. Ripley

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1 paper

Recent·Most cited

Enhanced ISGylation reduces respiratory distress following Francisella novicida infection

E. M. Upton, E. K. Luhmann, Y. Zhang, B. M. Ripley, D. K. Meyerholz, L. Radoshevich

This study shows that enhanced ISGylation reduces respiratory distress in Francisella novicida infection by modulating SAMHD1 function, suggesting USP18 inhibition as a therapeutic strategy.

bioRxiv · Sep 19, 2023 · PreprintMicrobiology