Optogenetic control of protein binding using light-switchable nanobodies
A. A. Gil, E. M. Zhao, M. Z. Wilson, A. G. Goglia, C. Carrasco-Lopez, J. L. Avalos, J. E. Toettcher
This paper develops opto-nanobodies (OptoNBs) that enable light-switchable binding to target proteins, showing applications in modulating signaling and protein purification.
bioRxiv · Aug 18, 2019Biochemistry