Author

M. Z. Wilson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:electronic health records· 1

Frequent Co-Authors

A. G. Goglia· 2 shared J. E. Toettcher· 2 shared A. A. Gil· 1 shared A. Bond· 1 shared A. Granados· 1 shared A. Mateus· 1 shared A. Mukherjee· 1 shared A. Typas· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

A. G. Goglia

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms

A. Bond, S. Fiaz, K. R. Rollins, J. E. Q. Nario, S. J. Rosen, A. Granados, M. Z. Wilson, M. A. Morrissey

This study shows that prior Fc receptor activation primes macrophages to be more sensitive to IgG, enhancing phagocytosis through short- and long-term mechanisms.

bioRxiv · Nov 14, 2023Cell Biology

Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields

S. Maity, B. D. Price, C. B. Wilson, A. Mukherjee, M. Starck, D. Parker, M. Z. Wilson, J. E. Lovett, S. Han, M. S. Sherwin

The paper introduces TiGGER, a time-resolved EPR method at high magnetic fields, to study protein mechanical dynamics, finding that light activation causes rapid separation and slow relaxation in AsLOV2.

bioRxiv · Oct 12, 2022Biophysics

Nucleation of the destruction complex on the centrosome accelerates degradation of β-catenin and regulates Wnt signal transmission

R. S. Lach, C. Qiu, E. Z. Kajbaf, N. J. Baxter, D. Han, A. Y. Wang, H. M. Lock, O. Chirikin, B. L. Pruitt, M. Z. Wilson

The paper shows that centrosome-nucleated biomolecular condensates of the Destruction Complex enhance β-catenin degradation and regulate Wnt signaling in human embryonic stem cells.

bioRxiv · Feb 1, 2022Cell Biology

A dual-mechanism antibiotic targets Gram-negative bacteria and avoids drug resistance

J. K. Martin, M. Z. Wilson, G. M. Moore, J. P. Sheehan, A. Mateus, S. H.-J. Li, B. P. Bratton, H. Kim, J. D. Rabinowitz, A. Typas, M. M. Savitski, Z. Gitai

This paper identifies a dual-mechanism antibiotic, SCH-79797, that kills Gram-negative and Gram-positive bacteria with low resistance and outperforms combination treatments.

Cell · Jun 1, 2020Peer-reviewedMicrobiology

Optogenetic control of protein binding using light-switchable nanobodies

A. A. Gil, E. M. Zhao, M. Z. Wilson, A. G. Goglia, C. Carrasco-Lopez, J. L. Avalos, J. E. Toettcher

This paper develops opto-nanobodies (OptoNBs) that enable light-switchable binding to target proteins, showing applications in modulating signaling and protein purification.

bioRxiv · Aug 18, 2019Biochemistry

A live-cell screen for altered Erk dynamics reveals principles of proliferative control

A. G. Goglia, M. Z. Wilson, J. Silbert, L. P. Basta, S. Jena, D. Devenport, J. E. Toettcher

The paper performs a live-cell screen of kinase inhibitors to identify modulators of Erk dynamics and shows how these dynamics affect cell proliferation.

bioRxiv · Jul 31, 2019Cell Biology