ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
S. Shrestha, A. Lamattina, G. Pacheco-Rodriguez, J. Ng, X. Liu, A. Sonawane, J. Imani, K. Kosmas, P. Louis, A. Hentschel, H. A. Christou, E. P. Henski, K. Glass, M. A. Perrella, J. Moss, , S. El-Chemaly
This study identifies ETV2 as a regulator of cell death in Tsc2-deficient cells through PARPBP and ER stress, suggesting a potential therapeutic target for LAM.
bioRxiv · Nov 8, 2021Cell Biology