Author

E. R. Siegel

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Tackett· 1 shared I. R. Miousse· 1 shared K. F. Wallis· 1 shared L. C. Morehead· 1 shared S. Garg· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. J. Tackett

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1 paper

Recent·Most cited

Increased response to immune checkpoint inhibitors with dietary methionine restriction

L. C. Morehead, S. Garg, K. F. Wallis, E. R. Siegel, A. J. Tackett, I. R. Miousse

This study shows that dietary methionine restriction enhances immune checkpoint inhibitor efficacy in mice by increasing MHC-I and PD-L1 expression via the cGAS-STING pathway and interferon signaling.

bioRxiv · Apr 5, 2023 · PreprintCancer Biology