Author

E. Rolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Galera-Prat· 1 shared J. P. Heiskanen· 1 shared L. Lehtiö· 1 shared M. M. Maksimainen· 1 shared S. Murthy· 1 shared S. T. Sowa· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Galera-Prat

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1 paper

Recent·Most cited

Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs

M. M. Maksimainen, S. Murthy, S. T. Sowa, A. Galera-Prat, E. Rolina, J. P. Heiskanen, L. Lehtiö

The paper develops TIQ-A analogs that selectively inhibit mono-ADP-ribosyltransferases PARP10 and PARP15 over poly-ADP-ribosyltransferases, achieving 10-20-fold selectivity while maintaining micromolar potency.

bioRxiv · Aug 30, 2021Biochemistry