A mosaic renal myeloid subtype with T-cell inhibitory and protumoral features is linked to immune escape and survival in clear cell renal cell cancer
D. Brech, T. Straub, E. Kokolakis, M. Irmler, J. Beckers, F. Buettner, E. Schaeffeler, S. Winter, M. Schwab, P. J. Nelson, E. Noessner
The paper identifies a renal myeloid subtype in clear cell renal cell cancer that exhibits immunoinhibitory and tumor-promoting features, correlates with poor patient survival, and suggests therapeutic targets.
bioRxiv · Jan 20, 2020 · PreprintImmunology