Author

M. Schwab

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Cellerino· 1 shared A. Königsrainer· 1 shared A. L. Birkenfeld· 1 shared A. Sahm· 1 shared A. Szewczyk· 1 shared A. Tolios· 1 shared B. Kulawiak· 1 shared B. Oswald· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. Cellerino

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Author profile →

4 papers

Recent·Most cited

mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

H. Bischof, S. Maier, P. Koprowski, B. Kulawiak, S. Burgstaller, J. Jasinska, K. Serafimov, M. Zochowska, D. Gross, W. Schroth, L. Matt, D. A. Juarez Lopez, Y. Zhang, I. Bonzheim, F. A. Büttner, , R. Lukowski

This study identifies mitoBKCa, a BKCa splice variant in mitochondria of breast cancer cells, showing it modulates energy production and promotes proliferation, suggesting it as a potential therapeutic target.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology

A mosaic renal myeloid subtype with T-cell inhibitory and protumoral features is linked to immune escape and survival in clear cell renal cell cancer

D. Brech, T. Straub, E. Kokolakis, M. Irmler, J. Beckers, F. Buettner, E. Schaeffeler, S. Winter, M. Schwab, P. J. Nelson, E. Noessner

The paper identifies a renal myeloid subtype in clear cell renal cell cancer that exhibits immunoinhibitory and tumor-promoting features, correlates with poor patient survival, and suggests therapeutic targets.

bioRxiv · Jan 20, 2020 · PreprintImmunology

Short-term oxaliplatin exposure according to established hyperthermic intraperitoneal chemotherapy (HIPEC) protocols lacks effectiveness in vitro and ex vivo

M. W. Löffler, N. Seyfried, M. Burkard, B. Oswald, A. Tolios, C. Yurttas, F. Herster, J. Kauer, T. Jäger, K. Thiel, S. P. Haen, H.-G. Rammensee, S. Venturelli, M. Schwab, A. Königsrainer, S. Beckert

This study shows that oxaliplatin-containing solutions during HIPEC protocols are ineffective in vitro and ex vivo, with low cytotoxicity and cell shrinkage observed.

bioRxiv · Jul 31, 2019 · PreprintPharmacology & Toxicology

Long-lived rodents reveal signatures of positive selection in genes associated with lifespan and eusociality

A. Sahm, M. Bens, K. Szafranski, S. Holtze, M. Groth, M. Goerlach, C. Calkhoven, C. Mueller, M. Schwab, H. A. Kestler, A. Cellerino, H. Burda, T. Hildebrandt, P. Dammann, M. Platzer

The paper identifies genes under positive selection in long-lived rodents, linking them to mTOR-related processes, immune function, and antioxidant defense, and finds expression patterns consistent with antagonistic pleiotropy in aging.

bioRxiv · Oct 8, 2017Evolutionary Biology