Author

L. Boutin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

L. Zhou· 2 shared M. T. Wilhelm· 2 shared A.-S. Oppelt· 1 shared C. Barjon· 1 shared D. Bourges· 1 shared E. Scotet· 1 shared E. Senechal· 1 shared E. Simon-Loriere· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

L. Zhou

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.

N. F. H. N. van Bree, A.-S. Oppelt, S. Lindstrom, L. Zhou, L. Boutin, J. I. Johnsen, L. Brautigam, M. T. Wilhelm

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.

bioRxiv · Feb 21, 2024Cancer Biology

High-throughput neural stem cell-based drug screening identifies S6K1 inhibition as a selective vulnerability in SHH-medulloblastoma

L. Zhou, N. van Bree, L. Boutin, S. Moussaud, M. Otrocka, M. T. Wilhelm

bioRxiv · Jan 31, 2024Cancer Biology

Targeting human γδ T cells as a potent and safe alternative to pan-T cells bispecific cell engagers

L. Boutin, C. Barjon, L. Lafrance, E. Senechal, D. Bourges, E. Vigne, E. Scotet

This study compares the antitumor activity of TCEs targeting conventional β T cells and unconventional γδ T cells, finding γδ T cells are more effective and safer.

bioRxiv · Jul 10, 2023Immunology

APOBEC3F is the main source of editing identified during the 2022 outbreak of human monkeypox virus

R. Suspene, K. A. Raymond, L. Boutin, S. Guillier, F. Lemoine, O. Ferraris, J.-N. Tournier, F. Iseni, E. Simon-Loriere, J.-P. Vartanian

The paper identifies APOBEC3F as the main source of hypermutation in MPXV during the 2022 outbreak, showing its role in generating G->A mutations and subsequent viral evolution.

bioRxiv · Jan 6, 2023 · PreprintMicrobiology