Author

E. Wierenga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

C. Stok· 2 shared M. Everts· 2 shared A. Audrey· 1 shared A. Bhattacharya· 1 shared A. M. Heijink· 1 shared A. Ray Chaudhuri· 1 shared D. C. J. Spierings· 1 shared D. Porubsky· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

C. Stok

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin.

C. Stok, N. van den Tempel, M. Everts, E. Wierenga, F. Bakker, Y. Kok, I. Teles Alves, L. Jae, A. Bhattacharya, E. Karanika, P. Perepelkina, S. Bergink, K.-L. Chan, R. de Boer, R. Fehrmann, M. van Vugt

The paper identifies C1orf112 as a synthetic lethal partner of PICH, showing it stabilizes FIGNL1 and regulates RAD51 retention on chromatin, impacting genome maintenance.

bioRxiv · Oct 7, 2022 · PreprintCancer Biology

Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors

A. M. Heijink, C. Stok, D. Porubsky, E. M. Manolika, Y. P. Kok, M. Everts, H. R. de Boer, A. Audrey, E. Wierenga, V. Guryev, D. C. J. Spierings, P. Knipscheer, A. Ray Chaudhuri, P. M. Lansdorp, M. A. T. M. van Vugt

This study shows PARP inhibitors induce sister chromatid exchanges (SCEs) through under-replicated DNA processed in mitosis, independent of homologous recombination factors.

bioRxiv · Sep 17, 2021 · PreprintCancer Biology