Author

E. Y. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Brodsky· 1 shared A. S. Siddique· 1 shared C. F. Maher· 1 shared C.-Y. Lim· 1 shared D. Yang· 1 shared E. D. Uzun· 1 shared H. R. Shin· 1 shared I. Y. Wong· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. S. Brodsky

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2 papers

Recent·Most cited

Somatic Mutations in Collagens are Associated with a Distinct Tumor Environment and Overall Survival in Gastric Cancer

A. S. Brodsky, J. Khurana, K. Guo, E. Y. Wu, D. Yang, A. S. Siddique, I. Y. Wong, E. D. Uzun, M. B. Resnick

This study identifies somatic collagen mutations in gastric cancer linked to distinct tumor environments and survival outcomes.

bioRxiv · Jan 19, 2021Cancer Biology

NPC1-mTORC1 signaling Couples Cholesterol Sensing to Organelle Homeostasis and is a Targetable Pathway in Niemann-Pick type C

O. B. Davis, H. R. Shin, C.-Y. Lim, E. Y. Wu, M. Kukurugya, C. F. Maher, R. M. Perera, P. Ordonez, R. Zoncu

This study identifies mTORC1 hyperactivation as a downstream driver of lysosomal dysfunction in NPC, showing that its inhibition can restore proteolysis and mitigate mitochondrial dysfunction.

bioRxiv · Aug 2, 2020Cell Biology