COVID-19 patients upregulate toll-like receptor 4-mediated inflammatory signaling that mimics bacterial sepsis
K. M. Sohn, S.-G. Lee, H. J. Kim, S. Cheon, H. Jeong, J. Lee, I. S. Kim, P. Silwal, Y. J. Kim, C. Park, Y.-S. Kim, E.-K. Jo
The paper identifies upregulated TLR4-mediated inflammatory signaling in COVID-19 patients, linking it to pathological inflammation and suggesting TLR4 as a therapeutic target.
bioRxiv · Jul 17, 2020Immunology