Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus
Yvonne X. Kong, Rajan Rehan, Cesar L. Moreno, Søren Madsen, Yunwei Zhang, Huiwen Zhao, Miao Qi, Callum B. Houlahan, Siân Peta Cartland, Declan Robertshaw, Vincent Trang, Frederick Jun Liang Ong, Michael Liu, Edward Cheng, Imala D. Alwis, , Freda H. Passam
This study identifies SEC61B as a regulator of calcium flux and platelet hyperreactivity in diabetes by linking ER stress to increased SEC61B expression and calcium leak.
Journal of Clinical Investigation · Aug 15, 2025Peer-reviewedCell Biology