Author

Siân Peta Cartland

The Heart Research InstituteORCID 0000-0003-1723-2679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mary Meltem KavurmaiD· 2 shared Alexander DupuyiD· 1 shared Alexander Ruvantha PintoiD· 1 shared Callum B. HoulahaniD· 1 shared Cesar L. MorenoiD· 1 shared Christina A. BursilliD· 1 shared Christopher P. StanleyiD· 1 shared David A Robinson· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

Mary Meltem KavurmaORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintSep 22, 2025

Mitochondrial Dysfunction in Endothelial Cells Drives Greater Vascular Impairment in Females with Diabetes-Associated Peripheral Artery Disease

Siân Peta Cartland, Elaina Kelland, Natalie Le…·Mary Meltem Kavurma

This study identifies sex-specific mitochondrial dysfunction in endothelial cells of diabetic PAD patients, showing that MitoQ improves vascular function in females.

DOI 10.1101/2025.09.22.677648

mousehuman

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Cell BiologyJournal of Clinical InvestigationPeer-reviewedAug 15, 2025

Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus

Yvonne X. Kong, Rajan Rehan, Cesar L. Moreno…·Freda H. Passam

This study identifies SEC61B as a regulator of calcium flux and platelet hyperreactivity in diabetes by linking ER stress to increased SEC61B expression and calcium leak.

12 citationstop 2%

humanmouse

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