Author

Edward J. O’Brien

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Organism:E. coli· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Colton J. LloydiD· 2 shared Zachary A. KingiD· 2 shared Adam M. FeistiD· 1 shared Ali EbrahimiD· 1 shared Bernhard Ørn PalssoniD· 1 shared Caitriona BrennaniD· 1 shared Connor A. OlsoniD· 1 shared Edward CatoiuiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Colton J. LloydORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedMar 1, 2019

Model-driven design and evolution of non-trivial synthetic syntrophic pairs

Colton J. Lloyd, Zachary A. King, Troy E. Sandberg…·Adam M. Feist

This paper designs and evolves synthetic syntrophic E. coli pairs using a novel algorithm, revealing metabolic changes that enhance community fitness and guide co-culture optimization.

32 citations

E. colimetagenomics

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedJul 5, 2018

COBRAme: A Computational Framework for Models of Metabolism and Gene Expression

Colton J. Lloyd, Ali Ebrahim, Laurence Yang…·Bernhard Ørn Palsson

COBRAme is a software framework for building and simulating ME-models, enabling efficient reconstruction and analysis of genome-scale models of metabolism and gene expression.

167 citationstop 2%

E. colimetabolomics

𝕏 PostBluesky