Author

Edward Mulkern

Mater Misericordiae University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aarushi SinghaliD· 1 shared Catherine GodsoniD· 1 shared Ciarán McDonnelliD· 1 shared Eoin Patrick BrennaniD· 1 shared Hanna EnglertiD· 1 shared Karran Kiran Bhagat· 1 shared Luiz Ricardo C. VasconcellosiD· 1 shared Manikandan SubramanianiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPathology

Aarushi SinghalORCID

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Author profile →

1 paper

Recent·Most cited

Impaired Macrophage DNase Secretion Promotes Neutrophil Extracellular Trap Mediated Defective Efferocytosis in Atherosclerosis

Umesh Kumar Dhawan, Tanwi Vartak, Hanna Englert, Aarushi Singhal, Rahul Chakraborty, Karran Kiran Bhagat, Luiz Ricardo C. Vasconcellos, Ciarán McDonnell, Mary Connolly, Edward Mulkern, Martin K. O’Donohoe, Mathias Gelderblom, Thomas Renné, Catherine Godson, Eoin Patrick Brennan, Manikandan Subramanian

This study identifies impaired macrophage DNase secretion due to ER stress as a mechanism leading to NET persistence and defective efferocytosis in atherosclerosis.

bioRxiv · Jan 30, 2025 · PreprintPathology