Artery-on-chip demonstrates smooth muscle function comparable to both healthy and diseased living tissues
Danielle Yarbrough, Roy Chen, Jaron Shoemaker, Edwin Yu, Jennifer Arthur Ataam, Connor D. Amelung, Ioannis Karakikes, Sharon Gerecht
The paper develops an artery-on-chip model using human iPSC-derived cells to replicate arterial function and disease states, showing comparable tissue mechanics and disease phenotypes.
bioRxiv · Mar 6, 2025 · PreprintBioengineering