Argonaute loss is associated with reduced endogenous leishbuvirid RNA abundance and disruption of viral small RNA accumulation in Leishmania martiniquensis
Grant A. Kay, Donnamae Klocek, Rhys H. Parry, Megan Byrne, Eilidh Campbell, Kristína Záhonová, Edubiel A. Alpizar-Sosa, Aitor Casas-Sánchez, Jovana Sádlová, Petr Volf, Vyacheslav Yurchenko, Alain Kohl
The paper investigates the role of Argonaute in controlling viral replication in Leishmania martiniquensis, finding that its loss reduces viral RNA abundance and disrupts small RNA accumulation.
bioRxiv · Oct 16, 2026 · PreprintMolecular Biology