Aitor Casas-Sánchez

Argonaute loss is associated with reduced endogenous leishbuvirid RNA abundance and disruption of viral small RNA accumulation in Leishmania martiniquensis

The paper investigates the role of Argonaute in controlling viral replication in Leishmania martiniquensis, finding that its loss reduces viral RNA abundance and disrupts small RNA accumulation.

Leishmania guyanensis controls endogenous viral replication by a canonical RNA interference pathway

This study identifies Dicer-like 1 and Argonaute 1 as critical for controlling viral RNA levels in Leishmania guyanensis via a canonical RNA interference pathway.

Dynamic Culture Improves the Predictive Power of Bronchial and Alveolar Airway Models of SARS-CoV-2 Infection

This study compares static and dynamic flow culture conditions in human airway models to show that dynamic flow improves tissue architecture, infection dynamics, and predictive power for SARS-CoV-2 infection.

Oxidative phosphorylation is required for powering motility and development of the sleeping sickness parasite Trypanosoma brucei within the tsetse fly vector

This study shows that oxidative phosphorylation is essential for Trypanosoma brucei migration within tsetse flies but not for initial colonization.

The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage

The paper identifies and characterizes a novel family of invariant surface proteins in the metacyclic stage of Trypanosoma brucei, suggesting a more permissive VSG coat structure that may aid vaccine development.